Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK

  • Kamilah Lewis
Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK. A. Kathrani, D. Werling, K. Allenspach. Veterinary Record (2011) 169, 635. Doi: 10.1136/vr.d5380. Five hundred and forty-six dogs with IBD were identified, representing 86 different breeds. The comparison group consisted of all dogs from these same 86 breeds without IBD admitted to the hospital during the same period that amounted to 27,463 dogs. The breeds at significantly higher risk of developing IBD compared with mixed-breed dogs consisted of Weimaraner (odds ratio [OR] =3.6797, 95 per cent confidence interval [CI] =2.0167 to 6.7141, P<0.0001), Rottweiler (OR=2.9697, 95 per cent CI=1.7569 to 5.0196, P<0.0001), German Shepherd dog (GSD) (OR=2.4101, 95 per cent CI=1.5826 to 3.36705, P<0.0001), Border collie (OR=1.9936, 95 per cent CI=1.1655 to 3.4101, P=0.0118) and Boxer (OR=1.6961, 95 per cent CI=1.0441 to 2.755, P=0.0328). This study demonstrates for the first time canine breeds in the south-eastern UK that are highly susceptible to developing IBD. Identification of such breeds may allow for a more focused investigation of genetic mutations associated with canine IBD. http://veterinaryrecord.bmj.com/content/169/24/635.info
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